Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | MAOB | P27338 | 12/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30132496 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTMAOBHTR2C | |
| Resorcinol SCHEMBL7096097 | 0.94 | ALDH1A1 (0.88) | ALDH1A1KDM4EMAPTMAOBHTR2C | |
| SCHEMBL1146916 | 0.87 | MAPT (1.00) | ALDH1A1KDM4EMAPTMAOBNPC1 | |
| SCHEMBL12478774 | 0.84 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTMAOBNPC1 | |
| SCHEMBL11369382 | 0.81 | KDM4E (0.68) | ALDH1A1KDM4EMAPTMAOBHTR2C | |
| SCHEMBL6385719 | 0.81 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTMAOBNPC1 | |
| SCHEMBL4728857 | 0.81 | KDM4E (0.69) | ALDH1A1KDM4EMAPTMAOBHTR2C | |
| SCHEMBL4727223 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTMAOBNPC1 | |
| SCHEMBL6552997 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTMAOBHTR2C | |
| SCHEMBL2319848 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4474446-B1 | ELECTROCHROMIC COMPOUNDS, COMPOSITIONS AND DEVICES COMPRISING THE SAME | ESSILOR INT (FR) | 2025-12-17 | — | — | EP | disclosed |
| US-20250042911-A1 | NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF | SPARK BIOPHARMA, INC. (KR) | 2025-02-06 | — | — | US | disclosed |
| WO-2024251948-A1 | ELECTROCHROMIC COMPOUNDS, COMPOSITIONS AND DEVICES COMPRISING THE SAME | ESSILOR INTERNATIONAL (FR) | 2024-12-12 | — | — | WO | disclosed |
| EP-4474446-A1 | ELECTROCHROMIC COMPOUNDS, COMPOSITIONS AND DEVICES COMPRISING THE SAME | Essilor International (FR) | 2024-12-11 | — | — | EP | disclosed |
| EP-4365175-A1 | NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF | Spark Biopharma, Inc. (KR) | 2024-05-08 | — | — | EP | disclosed |
| CN-117897386-A | Benzopyran derivatives and uses thereof | 斯帕克生物制药有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| WO-2023277656-A1 | NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF | (주)스파크바이오파마 | 2023-01-05 | — | — | WO | disclosed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | disclosed |
| US-11447471-B2 | α,β-unsaturated amide compound | KYOWA KIRIN CO., LTD. (JP) | 2022-09-20 | — | — | US | disclosed |
| US-RE30739-E | ANTIDEPRESSANT | BEECHAM GROUP LIMITED (GB) | 1981-09-08 | — | — | US | disclosed |
| EP-0028449-A1 | Chromanol derivatives, a process for their preparation and a pharmaceutical composition comprising them | BEECHAM GROUP PLC (GB) | 1981-05-13 | — | — | EP | disclosed |
| EP-0017352-A2 | Chromanone derivatives, a process for their preparation, compositions containing them | BEECHAM GROUP PLC (GB) | 1980-10-15 | — | — | EP | disclosed |
| US-4194029-A | Novel 4-chromanone-7-phosphates and phosphonates and the insecticidal use thereof | STAUFFER CHEMICAL COMPANY (US) | 1980-03-18 | — | — | US | disclosed |
| US-4167515-A | Anorexic chromans | BEECHAM GROUP LIMITED (GB) | 1979-09-11 | — | — | US | disclosed |
| US-4162326-A | ANTI-JUVENILE HORMONE | STAUFFER CHEMICAL COMPANY (US) | 1979-07-24 | — | — | US | disclosed |
| US-4153617-A | Anorexic chromans | BEECHAM GROUP LIMITED (GB) | 1979-05-08 | — | — | US | disclosed |
| US-4148909-A | Chromans to treat depression and reduce appetite | BEECHAM GROUP LIMITED (GB) | 1979-04-10 | — | — | US | disclosed |
| US-4146539-A | MOOD MODIFYERS, ANTIDEPRESSANTS | BEECHAM GROUP LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |
| US-4080335-A | Anorexic chromans | BEECHAM GROUP LIMITED (GB) | 1978-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11447471-B2 | α,β-unsaturated amide compound | NR1H2, RXRA, RXRB | ALDH1A1 683/4885KDM4E 4037/4885MAPT 4590/4885 |
| US-20250042911-A1 | NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF | MYD88, MYADM, CD14 | ALDH1A1 2146/4885KDM4E 588/4885MAPT 4729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.