Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893532 | 0.83 | BIRC5 (0.53) | CDC7CDK2ROCK1BIRC5CYP19A1 | |
| SCHEMBL695804 | 0.79 | CDC7 (0.39) | CDC7CDK2ROCK1CYP19A1GRM5 | |
| SCHEMBL30241499 | 0.77 | CDC7 (0.46) | CDC7CDK2ROCK1BIRC5MAPT | |
| SCHEMBL14268042 | 0.77 | CDC7 (0.46) | CDC7CDK2ROCK1BIRC5MAPT | |
| SCHEMBL6840216 | 0.76 | RXRA (0.48) | ROCK1MGLL | |
| SCHEMBL30774450 | 0.75 | BIRC5 (0.61) | CDC7CDK2ROCK1BIRC5CYP19A1 | |
| SCHEMBL1131757 | 0.75 | BIRC5 (0.61) | CDC7CDK2ROCK1BIRC5CYP19A1 | |
| SCHEMBL8892709 | 0.75 | BIRC5 (0.45) | CDC7CDK2ROCK1BIRC5CYP19A1 | |
| SCHEMBL11910172 | 0.75 | BIRC5 (0.60) | CDC7CDK2ROCK1BIRC5MAPT | |
| SCHEMBL14255124 | 0.75 | CDC7 (0.43) | CDC7CDK2ROCK1BIRC5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112930346-A | Novel compounds as NADPH oxidase inhibitors | 金其尤泰克斯瑞士股份有限公司 | 2021-06-08 | — | — | CN | claimed |
| CN-112930346-A | Novel compounds as NADPH oxidase inhibitors | 金其尤泰克斯瑞士股份有限公司 | 2021-06-08 | — | — | CN | disclosed |