Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | PPARA | Q07869 | 13/20 | 0.60 |
| ▸ | PPARG | P37231 | 12/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952897 | 0.89 | LMNA (0.69) | L3MBTL1LMNAMAPK1HTTPPARA | |
| SCHEMBL8825267 | 0.86 | L3MBTL1 (0.65) | L3MBTL1LMNAMAPK1HTTPPARA | |
| SCHEMBL14277943 | 0.84 | PPARA (0.56) | L3MBTL1LMNAMAPK1HTTPPARA | |
| SCHEMBL14277935 | 0.83 | PPARA (0.59) | L3MBTL1LMNAMAPK1HTTPPARA | |
| SCHEMBL14277939 | 0.83 | ESR1 (0.53) | L3MBTL1LMNAMAPK1HTTPPARA | |
| SCHEMBL4476864 | 0.81 | LMNA (0.69) | L3MBTL1LMNAMAPK1HTTPPARA | |
| SCHEMBL4476867 | 0.81 | LMNA (0.69) | L3MBTL1LMNAMAPK1HTTPPARA | |
| SCHEMBL14277950 | 0.81 | L3MBTL1 (0.57) | L3MBTL1LMNAHTTESR1SMN1; SMN2 | |
| SCHEMBL23635710 | 0.81 | LMNA (0.74) | L3MBTL1LMNAMAPK1HTTPPARA | |
| SCHEMBL2736632 | 0.81 | LMNA (0.74) | L3MBTL1LMNAMAPK1HTTPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354557-B | Preparation method and application of 3-phenyl-2-propylene-1-one O-n-butyl oxime | 大连理工大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-113354557-A | Preparation method and application of 3-phenyl-2-propylene-1-one O-n-butyl oxime | 大连理工大学 | 2021-09-07 | — | — | CN | disclosed |
| CN-113004169-A | Preparation method of 1, 3-diphenyl-2-butene-1-one O-n-butyl oxime | 大连理工大学 | 2021-06-22 | — | — | CN | disclosed |