Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28319788 | 0.79 | MEN1 (0.44) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL12203195 | 0.78 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28367585 | 0.77 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL26242422 | 0.77 | PTPN1 (0.37) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL26320501 | 0.76 | RAB9A (0.37) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL19010384 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KDM4ESMN1; SMN2MAPK1PDCD1 | |
| SCHEMBL12695627 | 0.75 | MAPT (0.49) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL19764761 | 0.74 | CA1 (0.41) | ALDH1A1KDM4ESMN1; SMN2MAPTLIMK1 | |
| SCHEMBL26254239 | 0.74 | PDCD1 (0.46) | ALDH1A1KDM4ESMN1; SMN2GAAMAPK1 | |
| SCHEMBL31276071 | 0.74 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112851608-B | Catalytic oxidation synthesis method of 2-diaryl methyl benzofuran compound | 浙江工业大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-112851608-A | Catalytic oxidation synthesis method of 2-diaryl methyl benzofuran compound | 浙江工业大学 | 2021-05-28 | — | — | CN | disclosed |