Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970063 | 0.84 | APP (0.94) | APPCYP19A1MAOBMAOANQO2 | |
| SCHEMBL4970060 | 0.84 | APP (0.94) | APPCYP19A1MAOBMAOANQO2 | |
| SCHEMBL7620783 | 0.84 | APP (0.94) | APPCYP19A1MAOBMAOANQO2 | |
| SCHEMBL7620786 | 0.84 | APP (0.94) | APPCYP19A1MAOBMAOANQO2 | |
| SCHEMBL8927226 | 0.81 | APP (1.00) | APPCYP19A1MAOBMAOANQO2 | |
| SCHEMBL9750082 | 0.81 | APP (1.00) | APPCYP19A1MAOBMAOANQO2 | |
| SCHEMBL9750087 | 0.81 | APP (1.00) | APPCYP19A1MAOBMAOANQO2 | |
| SCHEMBL2831093 | 0.81 | APP (1.00) | APPCYP19A1MAOBMAOANQO2 | |
| SCHEMBL10616469 | 0.81 | APP (1.00) | APPCYP19A1MAOBMAOANQO2 | |
| SCHEMBL9750157 | 0.81 | APP (1.00) | APPCYP19A1MAOBMAOANQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107412788-B | Novel compound for imaging Tau protein accumulated in brain | 国立研究开发法人量子科学技术研究开发机构 | 2021-06-18 | — | — | CN | disclosed |