SCHEMBL2858201

SCHEMBL2858201

CCOC(=O)C(Cl)C(Cl)C(=O)OCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
LMNA P02545 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ALOX15 P16050 1/20 0.46
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
SOAT1 P35610 1/20 0.46
TRPA1 O75762 1/20 0.42
PIN1 Q13526 1/20 0.38
HCAR2 Q8TDS4 1/20 0.37
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
KMT2A Q03164 1/20 0.36
CAD P27708 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TSHR P16473 1/20 0.36
GLO1 Q04760 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3626667 0.90 ALOX15 (0.50) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL27923771 0.90 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL28436976 0.89 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL10809179 0.87 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL8926364 0.87 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL2168277 0.85 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL16190581 0.85 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL19466095 0.85 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL2168275 0.85 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL28562629 0.85 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10ALOX15MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112064180-A Milk protein fiber and modal fiber blended fabric and preparation process thereof 成都吱吖科技有限公司 2020-12-11 CN claimed
CN-109928903-A Quantum dot surface ligand, quantum dot film and its preparation method and application TCL集团股份有限公司 2019-06-25 CN claimed
CN-117915740-A Optoelectronic device and electronic equipment TCL科技集团股份有限公司 2024-04-19 CN disclosed
CN-107759516-B Preparation method of alkyl ether substituted pyridine-2, 3-dicarboxylic acid derivative 沈阳化工研究院有限公司 2021-04-27 CN disclosed
CN-109935739-B Positive QLED device and preparation method thereof TCL科技集团股份有限公司 2021-04-09 CN disclosed
CN-112064180-A Milk protein fiber and modal fiber blended fabric and preparation process thereof 成都吱吖科技有限公司 2020-12-11 CN disclosed
CN-109935725-B Quantum dot light-emitting diode and preparation method and application thereof TCL科技集团股份有限公司 2020-08-14 CN disclosed
EP-1795581-B1 LUBRICATING OIL COMPOSITION CONTAINING ACRYLIC POLYMER KURARAY CO (JP) 2018-09-19 EP disclosed
CN-1984981-B Lubricating oil additive containing acrylic polymer and lubricating oil composition KURARAY CO 2010-11-17 CN disclosed
CN-1911896-B Process for producing benzopyrone compound SUMITOMO CHEMICAL CO 2010-09-15 CN disclosed
US-7718588-B2 Lubricating oil additive containing acrylic polymer and lubricating oil compositions KURARAY CO., LTD. (JP) 2010-05-18 US disclosed
US-4996350-A Solvent-free chlorination of dialkyl maleate; herbicide intermediates AMERICAN CYANAMID COMPANY (US) 1991-02-26 US disclosed
EP-0262305-B1 METHOD FOR THE PREPARATION OF ANILINOFUMARATE AND QUINOLINE-2,3-DICARBOXYLIC ACID AMERICAN CYANAMID COMPANY (US) 1990-10-31 EP disclosed
US-4847405-A AMINATION, PHASE TRANSFER AGENT AMERICAN CYANAMID COMPANY (US) 1989-07-11 US disclosed
EP-0309711-A1 Improved method for the preparation of anilinofumarate AMERICAN CYANAMID COMPANY (US) 1989-04-05 EP disclosed
EP-0309724-A1 Improved method for the preparation of dialkyl dichlorosuccinates AMERICAN CYANAMID COMPANY (US) 1989-04-05 EP disclosed
US-4814486-A FOR HERBICIDES AMERICAN CYANAMID COMPANY (US) 1989-03-21 US disclosed
US-4766218-A CYCLIZATION OF DICHLOROSUCCINATE WITH AMINE AMERICAN CYANAMID COMPANY (US) 1988-08-23 US disclosed
EP-0262305-A1 Method for the preparation of anilinofumarate and quinoline-2,3-dicarboxylic acid AMERICAN CYANAMID COMPANY (US) 1988-04-06 EP disclosed
US-4675432-A REACT DISHLOROSUCCINATE WITH ANILINE IN SOLVENT, BASE AND PHA SE TRANSFER CATALYST AMERICAN CYANAMID COMPANY (US) 1987-06-23 US disclosed