SCHEMBL2858670

SCHEMBL2858670

Cc1ccc(C(O)(c2ccc(C)cc2)C(O)(c2ccc(-c3ccccc3)cc2)c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.50
KIF11 P52732 1/20 0.46
PTPN5 P54829 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
HPGD P15428 2/20 0.44
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
NFKB1 P19838 1/20 0.44
RAB9A P51151 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
TSHR P16473 2/20 0.42
LMNA P02545 1/20 0.42
ALOX12 P18054 1/20 0.42
ACHE P22303 1/20 0.42
CYP1A2 P05177 1/20 0.41
MMP3 P08254 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2862802 0.89 MEN1 (0.50) KIF11SMN1; SMN2POLBMEN1KMT2A
SCHEMBL7768882 0.89 MEN1 (0.50) KIF11SMN1; SMN2POLBMEN1KMT2A
SCHEMBL2858210 0.86 CYP2C9 (0.58) CYP2C9KIF11PTPN5TDP1NPC1
SCHEMBL7763633 0.83 TSHR (0.55) TDP1NPC1RAB9AMEN1KMT2A
SCHEMBL22079642 0.81 ACHE (0.62) SMN1; SMN2TDP1HPGDNPC1POLB
SCHEMBL587 0.81 ACHE (0.62) SMN1; SMN2TDP1HPGDNPC1POLB
Tannin Pyrogallol SCHEMBL1419994 0.81 ACHE (0.62) SMN1; SMN2TDP1HPGDNPC1POLB
SCHEMBL7412470 0.81 ACHE (0.62) SMN1; SMN2TDP1HPGDNPC1POLB
P-Xylene SCHEMBL1419675 0.80 TSHR (0.68) CYP2C9KIF11PTPN5SMN1; SMN2TDP1
SCHEMBL10102374 0.79 CYP2C9 (0.43) CYP2C9KIF11PTPN5SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3597441-B1 METHOD OF PRODUCING A MULTILAYERED PRODUCT TRIP LICENSES BV (NL) 2021-04-28 EP disclosed
EP-3449315-B1 RADIATION CURABLE DRY TONER AND METHOD FOR PREPARING THE SAME XEIKON MFG NV (BE) 2021-03-31 EP disclosed
US-10919288-B2 Method of producing a multilayered product PROCRAFT DEVELOPMENT BV (NL) 2021-02-16 US disclosed
EP-3510058-A1 POLYMERIZING COMPOSITION, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME The University of Massachusetts (US) 2019-07-17 EP disclosed
US-20190202953-A1 POLYMERIZING COMPOSITION, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE UNIVERSITY OF MASSACHUSETTS 2019-07-04 US disclosed
US-20190129322-A1 Radiation Curable Dry Toner and Method for Preparing the Same XEIKON MANUFACTURING N.V. (BE) 2019-05-02 US disclosed
WO-2018039325-A1 POLYMERIZING COMPOSITION, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE UNIVERSITY OF MASSACHUSETTS (US) 2018-03-01 WO disclosed
US-7652128-B2 Toner composition XEROX CORPORATION (US) 2010-01-26 US disclosed
EP-1655323-B1 Toner composition XEROX CORP (US) 2010-01-20 EP disclosed
US-20060100300-A1 Toner composition XEROX CORPORATION 2006-05-11 US disclosed
US-4443495-A ETHYLENICALLY UNSATURATED COMPOUND AND A POLYTHIOL, SCREEN PRINTABLE W. R. GRACE & CO. (US) 1984-04-17 US disclosed
US-4406826-A POLYTHIOL, UNSATURATED MONOMER, METAL W. R. GRACE & CO. (US) 1983-09-27 US disclosed
US-4374963-A Heat curable epoxy-acrylate compositions W. R. GRACE & CO. (US) 1983-02-22 US disclosed
US-4352723-A ULTRAVIOLET RADIATION; PHOTOINITIATOR AND AROMATIC PINACOL W. R. GRACE & CO. (US) 1982-10-05 US disclosed
US-4288527-A Dual UV/thermally curable acrylate compositions with pinacol W. R. GRACE & CO. (US) 1981-09-08 US disclosed
US-4132812-A FREE RADICAL INITIATOR W. R. GRACE & CO. (US) 1979-01-02 US disclosed
US-4117017-A PROCESS FOR PREPARATION OF THIOLS USING A BENZOPINACOL INITIATOR W. R. GRACE & CO. (US) 1978-09-26 US disclosed
US-4117196-A PHOTOCURABLE IMIDIZABLE POLYENE-POLYTHIOL COMPOSITIONS W. R. GRACE & CO. (US) 1978-09-26 US disclosed
US-4080484-A POLYAMIDE-ACID OR POLYIMIDE W. R. GRACE & CO. (US) 1978-03-21 US disclosed
US-4020233-A Heat activated ethylenically unsaturated-polythiol compositions W. R. GRACE & CO. (US) 1977-04-26 US disclosed