Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28582220 | 1.00 | DRD2 (0.42) | DRD2DRD3NR1H2KCNA3RORC | |
| SCHEMBL28578409 | 0.85 | DRD2 (0.42) | DRD2NR1H2KCNA3RORCKDM4D | |
| SCHEMBL30180740 | 0.85 | DRD2 (0.42) | DRD2NR1H2KCNA3RORCKDM4D | |
| SCHEMBL28580143 | 0.85 | DRD2 (0.44) | DRD2DRD3NR1H2KCNA3KDM4D | |
| SCHEMBL30180649 | 0.85 | DRD2 (0.44) | DRD2DRD3NR1H2KCNA3KDM4D | |
| SCHEMBL28580140 | 0.85 | DRD2 (0.44) | DRD2DRD3NR1H2KCNA3KDM4D | |
| SCHEMBL28916241 | 0.84 | ALOX5 (0.43) | DRD2NR1H2RORCEPHX2 | |
| SCHEMBL30180547 | 0.84 | ALOX5 (0.43) | DRD2NR1H2RORCEPHX2 | |
| SCHEMBL28575235 | 0.82 | DRD2 (0.44) | DRD2DRD3KCNA3KDM4D | |
| SCHEMBL28575236 | 0.82 | DRD2 (0.44) | DRD2DRD3KCNA3KDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |