SCHEMBL2858291

SCHEMBL2858291

Cc1ccc(C(C)(C)C)c(O)c1.OP(O)O.OP(O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
ALOX15 P16050 6/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
MAPT P10636 3/20 0.52
CYP1A2 P05177 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ATP2A2 P16615 1/20 0.52
ATP2A3 Q93084 1/20 0.52
TRPA1 O75762 2/20 0.50
TDP1 Q9NUW8 3/20 0.46
CA2 P00918 3/20 0.46
TYR P14679 2/20 0.46
POLB P06746 2/20 0.46
TSHR P16473 2/20 0.46
LMNA P02545 4/20 0.43
HSD17B10 Q99714 3/20 0.43
CYP2C9 P11712 3/20 0.43
NR1I2 O75469 1/20 0.43
MIF P14174 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28683684 1.00 ALDH1A1 (0.52) ALDH1A1ALOX15SMN1; SMN2MAPTCYP1A2
SCHEMBL11656413 1.00 ALDH1A1 (0.52) ALDH1A1ALOX15SMN1; SMN2MAPTCYP1A2
SCHEMBL15485283 0.93 ALDH1A1 (0.59) ALDH1A1ALOX15SMN1; SMN2MAPTCYP1A2
SCHEMBL180815 0.93 ALDH1A1 (0.59) ALDH1A1ALOX15SMN1; SMN2MAPTCYP1A2
SCHEMBL29362726 0.93 ALDH1A1 (0.59) ALDH1A1ALOX15SMN1; SMN2MAPTCYP1A2
SCHEMBL28395985 0.92 ALDH1A1 (0.48) ALDH1A1ALOX15SMN1; SMN2MAPTCYP1A2
SCHEMBL30211783 0.91 ALDH1A1 (0.56) ALDH1A1ALOX15SMN1; SMN2MAPTCYP1A2
Potassium SCHEMBL29477970 0.91 ALDH1A1 (0.56) ALDH1A1ALOX15SMN1; SMN2MAPTCYP1A2
Hydrogen Sulfide SCHEMBL28854683 0.91 ALDH1A1 (0.56) ALDH1A1ALOX15SMN1; SMN2MAPTCYP1A2
SCHEMBL29477942 0.91 ALDH1A1 (0.56) ALDH1A1ALOX15SMN1; SMN2MAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2301924-B1 METHOD FOR PRODUCING 2,4,6-TRIS(HYDROXYPHENYL)-1,3,5-TRIAZINE COMPOUND ADEKA CORP (JP) 2015-09-02 EP disclosed
EP-2573076-B1 Method for producing 2,4,6-tris(hydroxyphenyl)-1,3,5-triazine compound ADEKA CORP (JP) 2014-08-20 EP disclosed
US-8716474-B2 Method for producing 2,4,6-tris(hydroxyphenyl)-1,3,5-triazine compound ADEKA CORPORATION (JP) 2014-05-06 US disclosed
EP-2573076-A1 Method for producing 2,4,6-tris(hydroxyphenyl)-1,3,5-triazine compound Adeka Corporation (JP) 2013-03-27 EP disclosed
US-7767313-B2 Polypropylene composite film comprising a metallocene-catalyzed propylene/1-butene random copolymer MITSUI CHEMICALS, INC. (JP) 2010-08-03 US disclosed
US-7737239-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-06-15 US disclosed
US-7678934-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-03-16 US disclosed
US-20080312461-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-18 US disclosed
US-20080306234-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-11 US disclosed
US-20080306219-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-11 US disclosed
US-20080292896-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-11-27 US disclosed
EP-0474889-B1 PROCESS FOR THERMAL DEGRADATION OF POLYMER MITSUI PETROCHEMICAL IND (JP) 1998-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312461-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST PPIA, PPOX, PTGES2 ALDH1A1 3243/4885ALOX15 70/4885SMN1; SMN2 2509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.