1-Naphthoquinoline

1-Naphthoquinoline

SCHEMBL28583281

[BeH2].c1ccc2c(c1)ccc1cccnc12.c1ccc2c(c1)ccc1cccnc12

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.67
CCR1 P32246 5/20 0.65
CCR8 P51685 5/20 0.65
CCR5 P51681 3/20 0.65
KDM4E B2RXH2 3/20 0.65
MAPT P10636 3/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
TSHR P16473 3/20 0.65
CYP3A4 P08684 2/20 0.65
TP53 P04637 2/20 0.65
MMP2 P08253 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
HSP90AA1 P07900 2/20 0.65
HIF1A Q16665 2/20 0.65
GMNN O75496 1/20 0.65
CYP2D6 P10635 1/20 0.65
MMP9 P14780 1/20 0.65
ALOX15 P16050 1/20 0.65
NFKB1 P19838 1/20 0.65
MMP8 P22894 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthoquinoline SCHEMBL28190950 1.00 LMNA (0.67) LMNACCR1CCR8CCR5KDM4E
1-Naphthoquinoline SCHEMBL27725047 0.98 LMNA (0.64) LMNACCR1CCR8CCR5KDM4E
1-Naphthoquinoline SCHEMBL29533982 0.98 LMNA (0.69) LMNACCR1CCR8CCR5KDM4E
1-Naphthoquinoline SCHEMBL15106 0.98 LMNA (0.69) LMNACCR1CCR8CCR5KDM4E
1-Naphthoquinoline SCHEMBL5572864 0.95 LMNA (0.67) LMNACCR1CCR8CCR5KDM4E
1-Naphthoquinoline SCHEMBL31286254 0.95 LMNA (0.67) LMNACCR1CCR8CCR5KDM4E
1-Naphthoquinoline SCHEMBL3045500 0.95 LMNA (0.67) LMNACCR1CCR8CCR5KDM4E
SCHEMBL3193877 0.95 LMNA (0.67) LMNACCR1CCR8CCR5KDM4E
1-Naphthoquinoline SCHEMBL262791 0.95 LMNA (0.67) LMNACCR1CCR8CCR5KDM4E
1-Naphthoquinoline SCHEMBL6340901 0.95 LMNA (0.67) LMNACCR1CCR8CCR5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107579093-B Organic light emitting display device 三星显示有限公司 2023-05-26 CN disclosed
CN-107565036-B Organic light emitting device 三星显示有限公司 2021-06-29 CN disclosed