SCHEMBL2858359

SCHEMBL2858359

CC(O)(c1ccccc1)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
ALOX15 P16050 1/20 0.46
ESR1 P03372 3/20 0.44
ESR2 Q92731 3/20 0.44
CYP3A4 P08684 2/20 0.44
MAPK1 P28482 2/20 0.44
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
CYP2C19 P33261 2/20 0.41
HIF1A Q16665 1/20 0.41
HSD11B1 P28845 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1617443 0.86 ALDH1A1 (0.52) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL14443430 0.81 ALDH1A1 (0.48) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL416036 0.81 ALDH1A1 (0.48) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL4082774 0.81 ALDH1A1 (0.48) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL8579900 0.81 ALDH1A1 (0.48) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL15275691 0.81 ALDH1A1 (0.48) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL3683859 0.81 ALDH1A1 (0.48) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL29199451 0.81 ALDH1A1 (0.48) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL7173455 0.80 CYP1A2 (0.48) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL36629 0.80 CYP1A2 (0.48) ALDH1A1ALOX15ESR1ESR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3597441-B1 METHOD OF PRODUCING A MULTILAYERED PRODUCT TRIP LICENSES BV (NL) 2021-04-28 EP disclosed
EP-3449315-B1 RADIATION CURABLE DRY TONER AND METHOD FOR PREPARING THE SAME XEIKON MFG NV (BE) 2021-03-31 EP disclosed
US-10919288-B2 Method of producing a multilayered product PROCRAFT DEVELOPMENT BV (NL) 2021-02-16 US disclosed
US-20190202953-A1 POLYMERIZING COMPOSITION, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE UNIVERSITY OF MASSACHUSETTS 2019-07-04 US disclosed
US-20190129322-A1 Radiation Curable Dry Toner and Method for Preparing the Same XEIKON MANUFACTURING N.V. (BE) 2019-05-02 US disclosed
US-7652128-B2 Toner composition XEROX CORPORATION (US) 2010-01-26 US disclosed
EP-1655323-B1 Toner composition XEROX CORP (US) 2010-01-20 EP disclosed
US-20060100300-A1 Toner composition XEROX CORPORATION 2006-05-11 US disclosed
EP-1655323-A2 Toner composition Xerox Corporation (US) 2006-05-10 EP disclosed
US-6545064-B1 Improved printability and other surface characteristics. AVERY DENNISON CORPORATION 2003-04-08 US disclosed
US-4443495-A ETHYLENICALLY UNSATURATED COMPOUND AND A POLYTHIOL, SCREEN PRINTABLE W. R. GRACE & CO. (US) 1984-04-17 US disclosed
US-4406826-A POLYTHIOL, UNSATURATED MONOMER, METAL W. R. GRACE & CO. (US) 1983-09-27 US disclosed
US-4374963-A Heat curable epoxy-acrylate compositions W. R. GRACE & CO. (US) 1983-02-22 US disclosed
US-4352723-A ULTRAVIOLET RADIATION; PHOTOINITIATOR AND AROMATIC PINACOL W. R. GRACE & CO. (US) 1982-10-05 US disclosed
US-4288527-A Dual UV/thermally curable acrylate compositions with pinacol W. R. GRACE & CO. (US) 1981-09-08 US disclosed
US-4132812-A FREE RADICAL INITIATOR W. R. GRACE & CO. (US) 1979-01-02 US disclosed
US-4117196-A PHOTOCURABLE IMIDIZABLE POLYENE-POLYTHIOL COMPOSITIONS W. R. GRACE & CO. (US) 1978-09-26 US disclosed
US-4117017-A PROCESS FOR PREPARATION OF THIOLS USING A BENZOPINACOL INITIATOR W. R. GRACE & CO. (US) 1978-09-26 US disclosed
US-4080484-A POLYAMIDE-ACID OR POLYIMIDE W. R. GRACE & CO. (US) 1978-03-21 US disclosed
US-4020233-A Heat activated ethylenically unsaturated-polythiol compositions W. R. GRACE & CO. (US) 1977-04-26 US disclosed