Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1617443 | 0.88 | ALDH1A1 (0.52) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL416036 | 0.83 | ALDH1A1 (0.48) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL14443430 | 0.83 | ALDH1A1 (0.48) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL3683859 | 0.83 | ALDH1A1 (0.48) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL2858359 | 0.81 | ALDH1A1 (0.46) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL28174698 | 0.80 | ALDH1A1 (0.50) | ALDH1A1ALOX15ESR1ESR2CYP3A4 | |
| SCHEMBL9888614 | 0.79 | HSD11B1 (0.63) | ALDH1A1ALOX15HSD11B1TSHR | |
| SCHEMBL9888655 | 0.79 | HSD11B1 (0.63) | ALDH1A1ALOX15HSD11B1TSHR | |
| SCHEMBL5354310 | 0.79 | HSD11B1 (0.63) | ALDH1A1ALOX15HSD11B1TSHR | |
| SCHEMBL29199451 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ALOX15ESR1ESR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599463-A | Process for the preparation of bisphenols | GENERAL ELECTRIC COMPANY (US) | 1986-07-08 | — | — | US | claimed |
| US-20180215783-A1 | BIOORTHOGONAL REACTION OF AN AMINE N-OXIDE AND A BORON AGENT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-08-02 | — | — | US | disclosed |
| US-20180215783-A1 | BIOORTHOGONAL REACTION OF AN AMINE N-OXIDE AND A BORON AGENT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-08-02 | — | — | US | disclosed |
| WO-2017027337-A1 | BIOORTHOGONAL REACTION OF AN AMINE N-OXIDE AND A BORON AGENT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-16 | — | — | WO | disclosed |
| US-7485413-B2 | Photosensitive composition and method for forming pattern using same | KABUSHIKI KAISHA TOSHIBA (JP) | 2009-02-03 | — | — | US | disclosed |
| US-7476488-B2 | Photosensitive composition and method for forming pattern using same | KABUSHIKI KAISHA TOSHIBA (JP) | 2009-01-13 | — | — | US | disclosed |
| US-7338755-B2 | Photosensitive composition and method for forming pattern using same | KABUSHIKI KAISHA TOSHIBA (JP) | 2008-03-04 | — | — | US | disclosed |
| US-20070238050-A1 | PHOTOSENSITIVE COMPOSITION AND METHOD FOR FORMING PATTERN USING SAME | KABUSHIKI KAISHA TOSHIBA (JP) | 2007-10-11 | — | — | US | disclosed |
| US-20070224550-A1 | PHOTOSENSITIVE COMPOSITION AND METHOD FOR FORMING PATTERN USING SAME | KABUSHIKI KAISHA TOSHIBA (JP) | 2007-09-27 | — | — | US | disclosed |
| US-20070224549-A1 | PHOTOSENSITIVE COMPOSITION AND METHOD FOR FORMING PATTERN USING SAME | KABUSHIKI KAISHA TOSHIBA (JP) | 2007-09-27 | — | — | US | disclosed |
| US-7241554-B2 | Photosensitive composition and method for forming pattern using same | KABUSHIKI KAISHA TOSHIBA (JP) | 2007-07-10 | — | — | US | disclosed |
| US-20060003254-A1 | Photosensitive composition and method for forming pattern using same | KABUSHIKI KAISHA TOSHIBA (JP) | 2006-01-05 | — | — | US | disclosed |
| US-6177229-B1 | COMPRISING ALKALI SOLUBLE RESIN HAVING ALKALI SOLUBLE GROUPS PROTECTED BY SUBSTITUENT DECOMPOSED BY ACID, A COMPOUND WHICH GENERATES ACID UPON IRRADIATION WITH ACTINIC RADIATION, AND A COMPOUND WHICH GENERATES WATER UNDER ACTION OF ACID CATALYST | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-01-23 | — | — | US | disclosed |
| US-4599463-A | Process for the preparation of bisphenols | GENERAL ELECTRIC COMPANY (US) | 1986-07-08 | — | — | US | disclosed |
| US-4207419-A | BRONCHODILATORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215783-A1 | BIOORTHOGONAL REACTION OF AN AMINE N-OXIDE AND A BORON AGENT | BBOX1, BLVRB, BTD | ALDH1A1 2904/4885ALOX15 440/4885ESR1 920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.