Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6716071 | 0.82 | TTK (0.53) | POLBMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL28613983 | 0.82 | TTK (0.53) | POLBMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL6827394 | 0.79 | POLB (0.53) | POLBMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL3456848 | 0.78 | KCNQ2 (0.64) | POLBMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL11620551 | 0.78 | ALDH1A1 (0.73) | POLBMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL10668212 | 0.78 | POLB (0.57) | POLBMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL28920993 | 0.77 | POLB (0.51) | POLBMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL1008398 | 0.77 | POLB (0.63) | POLBMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL28577403 | 0.76 | HTT (0.55) | POLBMAPK1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL28589799 | 0.76 | KCNQ2 (0.61) | POLBMAPK1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778154-B | Aryl alkyl ether compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-112778154-A | Aryl alkyl ether compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2021-05-11 | — | — | CN | disclosed |