Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827394 | 0.89 | POLB (0.53) | POLBMAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL8344864 | 0.81 | POLB (0.62) | POLBMAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL28613983 | 0.80 | TTK (0.53) | POLBMAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL6716071 | 0.80 | TTK (0.53) | POLBMAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL6715497 | 0.79 | ALDH1A1 (0.55) | POLBMAPK1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6714152 | 0.79 | ULK1 (0.53) | POLBMAPK1ALDH1A1KMT2AGAA | |
| SCHEMBL28920385 | 0.79 | POLB (0.56) | POLBMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL28617495 | 0.79 | KDM4E (0.48) | POLBMAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL29958946 | 0.79 | GRIN2D (0.60) | POLBMAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL167598 | 0.79 | GRIN2D (0.60) | POLBMAPK1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041285-B | Preparation method of 2, 4, 5-trisubstituted oxazole compound | 大连理工大学 | 2021-08-20 | — | — | CN | disclosed |