Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | PTAFR | P25105 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855300 | 0.94 | LTB4R2 (0.38) | HDAC1PTGS2 | |
| SCHEMBL2859541 | 0.91 | LTB4R2 (0.36) | PTGS2 | |
| SCHEMBL2847841 | 0.91 | LTB4R2 (0.38) | HDAC1PTGS2 | |
| SCHEMBL2849456 | 0.90 | LTB4R2 (0.37) | HDAC1PTGS2 | |
| SCHEMBL2854102 | 0.90 | LTB4R2 (0.37) | HDAC1PTGS2 | |
| SCHEMBL2849758 | 0.89 | LTB4R2 (0.36) | HDAC1PTGS2 | |
| SCHEMBL2854523 | 0.85 | LTB4R2 (0.34) | HDAC1PTGS2 | |
| SCHEMBL2858447 | 0.83 | PPARG (0.43) | — | |
| SCHEMBL2851855 | 0.83 | TACR2 (0.38) | — | |
| SCHEMBL2852386 | 0.81 | PPARG (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575911-B1 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2010-01-13 | — | — | EP | claimed |