Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.45 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849758 | 0.88 | LTB4R2 (0.36) | PPARG | |
| SCHEMBL2849456 | 0.88 | LTB4R2 (0.37) | PPARGPPARA | |
| SCHEMBL2854102 | 0.88 | LTB4R2 (0.37) | PPARGPPARA | |
| SCHEMBL2855300 | 0.86 | LTB4R2 (0.38) | PPARGPPARA | |
| SCHEMBL2847841 | 0.85 | LTB4R2 (0.38) | PPARGPPARA | |
| SCHEMBL2859541 | 0.84 | LTB4R2 (0.36) | PPARG | |
| SCHEMBL2851855 | 0.82 | TACR2 (0.38) | — | |
| SCHEMBL2858449 | 0.81 | ROCK2 (0.38) | — | |
| SCHEMBL2854523 | 0.81 | LTB4R2 (0.34) | PPARGPPARA | |
| SCHEMBL5361591 | 0.74 | SIRT2 (0.41) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575911-B1 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2010-01-13 | — | — | EP | claimed |