Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855300 | 0.91 | LTB4R2 (0.38) | LTB4R2PTGS2PTPN1PPARGNAAA | |
| SCHEMBL2847841 | 0.90 | LTB4R2 (0.38) | LTB4R2PTGS2PTPN1PPARGNAAA | |
| SCHEMBL2849456 | 0.89 | LTB4R2 (0.37) | LTB4R2PTGS2PTPN1PPARGNAAA | |
| SCHEMBL2854102 | 0.89 | LTB4R2 (0.37) | LTB4R2PTGS2PTPN1PPARGNAAA | |
| SCHEMBL2849758 | 0.87 | LTB4R2 (0.36) | LTB4R2PTGS2PTPN1PPARGNAAA | |
| SCHEMBL2859541 | 0.87 | LTB4R2 (0.36) | LTB4R2PTGS2PTPN1PPARGNAAA | |
| SCHEMBL2858449 | 0.85 | ROCK2 (0.38) | PTGS2HDAC1 | |
| SCHEMBL2851855 | 0.83 | TACR2 (0.38) | ALOX15SIRT2SIRT1 | |
| SCHEMBL2854521 | 0.81 | PPARG (0.41) | PPARGPPARA | |
| SCHEMBL2852386 | 0.81 | PPARG (0.45) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575911-B1 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2010-01-13 | — | — | EP | claimed |