Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 4/20 | 0.40 |
| ▸ | CTSD | P07339 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855184 | 0.89 | KDM4E (0.46) | SSTR3KDM4EALDH1A1HDAC1HDAC6 | |
| SCHEMBL2857395 | 0.86 | KDM4E (0.48) | KDM4EALDH1A1HDAC1HDAC6BACE1 | |
| SCHEMBL13711749 | 0.80 | KDM4E (0.48) | SSTR3KDM4EALDH1A1HDAC1HDAC6 | |
| SCHEMBL5598540 | 0.79 | KDM4E (0.41) | SSTR3KDM4EALDH1A1HDAC1HDAC6 | |
| SCHEMBL2853430 | 0.77 | TAOK1 (0.48) | KDM4EALDH1A1BACE1CTSD | |
| SCHEMBL2853647 | 0.72 | NSD2 (0.38) | SSTR3MEN1KMT2A | |
| SCHEMBL785333 | 0.70 | KMT2A (0.49) | SSTR3KDM4EMEN1KMT2ADHODH | |
| SCHEMBL785332 | 0.70 | KMT2A (0.49) | SSTR3KDM4EMEN1KMT2ADHODH | |
| SCHEMBL13945234 | 0.70 | KDM4E (0.47) | SSTR3KDM4EALDH1A1 | |
| SCHEMBL18023358 | 0.70 | HDAC1 (0.51) | SSTR3ALDH1A1HDAC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654247-B1 | ALKYNYL ARYL CARBOXAMIDES | MERCK SERONO SA (CH) | 2010-01-20 | — | — | EP | claimed |