Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598085 | 0.87 | KDM4E (0.41) | KDM4EALDH1A1HDAC1HDAC6 | |
| SCHEMBL2858467 | 0.79 | SSTR3 (0.48) | KDM4ESSTR3ALDH1A1HDAC1HDAC6 | |
| SCHEMBL2855184 | 0.74 | KDM4E (0.46) | KDM4ESSTR3ALDH1A1HDAC1HDAC6 | |
| SCHEMBL13711749 | 0.65 | KDM4E (0.48) | KDM4ESSTR3ALDH1A1HDAC1HDAC6 | |
| SCHEMBL6254168 | 0.62 | KDM4E (0.57) | KDM4EALDH1A1KMT2A | |
| SCHEMBL18023358 | 0.61 | HDAC1 (0.51) | SSTR3ALDH1A1HDAC1KMT2A | |
| SCHEMBL6419613 | 0.61 | RXRA (0.46) | KDM4EALDH1A1METAP2CYP1A2 | |
| SCHEMBL5461934 | 0.60 | PRMT5 (0.69) | GAA | |
| SCHEMBL17605620 | 0.60 | BCHE (0.52) | SSTR3ALDH1A1HDAC1SMN1; SMN2KMT2A | |
| SCHEMBL17605618 | 0.60 | BCHE (0.52) | SSTR3ALDH1A1HDAC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105913-A1 | Alkynyl aryl carboxamides | APPLIED RESEARCH SYSTEMS ARS HOLDINGS N.V. (NL) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105913-A1 | Alkynyl aryl carboxamides | ECHS1, IRS1, HCCS | KDM4E 1973/4885SSTR3 1840/4885ALDH1A1 1454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.