Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856521 | 0.91 | HMGCR (0.33) | HMGCR | |
| SCHEMBL2859655 | 0.88 | — | — | |
| SCHEMBL2853794 | 0.84 | TAS1R3 (0.34) | — | |
| SCHEMBL2851523 | 0.84 | SLC1A2 (0.32) | CA1CA2CA4 | |
| SCHEMBL2855823 | 0.81 | ALOX5 (0.43) | — | |
| SCHEMBL2851494 | 0.79 | — | — | |
| SCHEMBL2862668 | 0.78 | — | — | |
| SCHEMBL2859880 | 0.75 | TAS1R3 (0.31) | — | |
| SCHEMBL2855697 | 0.75 | ALOX5 (0.45) | — | |
| SCHEMBL2853489 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010072712-A1 | BIARYL BENZYLAMINE DERIVATIVES | NOVARTIS AG (CH) | 2010-07-01 | — | — | WO | disclosed |