Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 10/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLG | P54098 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177653 | 0.79 | MEN1 (0.74) | PNPMEN1KMT2AHBBMAPK1 | |
| SCHEMBL2434143 | 0.78 | PNP (0.57) | PNPMEN1KMT2AHBBMAPK1 | |
| SCHEMBL2861664 | 0.78 | PNP (0.52) | PNPMEN1KMT2AHBBMAPK1 | |
| SCHEMBL9566544 | 0.74 | PNP (0.71) | PNPMEN1KMT2AHBBMAPK1 | |
| SCHEMBL8781905 | 0.70 | PNP (0.55) | PNPMEN1KMT2AHBBMAPK1 | |
| SCHEMBL456162 | 0.69 | MAPK1 (0.44) | PNPMEN1KMT2AHBBMAPK1 | |
| SCHEMBL11008541 | 0.67 | PNP (0.46) | PNPMEN1KMT2AHBBMAPK1 | |
| SCHEMBL31043036 | 0.67 | PNP (0.78) | PNPMEN1KMT2AHBBUSP2 | |
| SCHEMBL1177556 | 0.67 | MEN1 (0.66) | PNPMEN1KMT2AHBBMAPK1 | |
| SCHEMBL453174 | 0.66 | PNP (0.49) | PNPMEN1KMT2AHBBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142548-B1 | ACYLATED DERIVATIVE OF THE PURINIC ANTIVIRAL AGENT ACICLOVIR AND USE THEREOF AS A POTENT ANTICANCER AGENT | UNIV RAMOT (IL) | 2016-05-25 | — | — | EP | disclosed |
| EP-2142548-A1 | NOVEL DERIVATIVES OF PURINIC AND PYRIMIDINIC ANTIVIRAL AGENTS AND USE THEREOF AS POTENT ANTICANCER AGENTS | Ramot at Tel-Aviv University Ltd. (IL) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008120205-A1 | NOVEL DERIVATIVES OF PURINIC AND PYRIMIDINIC ANTIVIRAL AGENTS AND USE THEREOF AS POTENT ANTICANCER AGENTS | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2008-10-09 | — | — | WO | disclosed |