Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 15/20 | 0.71 |
| ▸ | HBB | P68871 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | EDNRA | P25101 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2434143 | 0.90 | PNP (0.57) | PNPHBBUSP2TSHREDNRA | |
| SCHEMBL31043036 | 0.82 | PNP (0.78) | PNPHBBUSP2TSHREDNRA | |
| SCHEMBL11008541 | 0.80 | PNP (0.46) | PNPHBBUSP2TSHREDNRA | |
| SCHEMBL7200361 | 0.78 | PNP (0.46) | PNPHBBUSP2TSHREDNRA | |
| SCHEMBL8165565 | 0.78 | PNP (0.51) | PNPHBBUSP2TSHREDNRA | |
| SCHEMBL2861664 | 0.76 | PNP (0.52) | PNPHBBUSP2TSHREDNRA | |
| SCHEMBL8165318 | 0.75 | PNP (0.70) | PNPTSHRHSD17B10MEN1KMT2A | |
| Acyclovir SCHEMBL8986626 | 0.74 | PNP (0.79) | PNPHBBUSP2TSHREDNRA | |
| SCHEMBL7806050 | 0.74 | PNP (0.47) | PNPUSP2BLMMEN1KMT2A | |
| SCHEMBL2858495 | 0.74 | PNP (0.53) | PNPHBBUSP2TSHREDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564006-A2 | Process for preparing purine derivatives and novel purine derivatives | KRKA, tovarna zdravil, n.sol.o (YU) | 1993-10-06 | — | — | EP | claimed |
| EP-0289992-A2 | Process for preparing purine derivates | KEMIJSKI INSTITUT (SI) | 1988-11-09 | — | — | EP | claimed |
| EP-0564006-A2 | Process for preparing purine derivatives and novel purine derivatives | KRKA, tovarna zdravil, n.sol.o (YU) | 1993-10-06 | — | — | EP | disclosed |
| EP-0564006-A2 | Process for preparing purine derivatives and novel purine derivatives | KRKA, tovarna zdravil, n.sol.o (YU) | 1993-10-06 | — | — | EP | disclosed |
| EP-0289992-A2 | Process for preparing purine derivates | KEMIJSKI INSTITUT (SI) | 1988-11-09 | — | — | EP | disclosed |