Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25156033 | 0.86 | IMPDH2 (0.58) | IMPDH2ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL30344860 | 0.86 | IMPDH2 (0.58) | IMPDH2ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL28580528 | 0.84 | IMPDH2 (0.49) | IMPDH2SLC6A2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2146801 | 0.81 | IMPDH2 (0.51) | IMPDH2ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL14255223 | 0.79 | HTT (0.45) | IMPDH2SLC6A2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10190993 | 0.77 | IMPDH2 (0.51) | IMPDH2ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL1078113 | 0.77 | L3MBTL1 (0.53) | IMPDH2MAPT | |
| SCHEMBL18979158 | 0.77 | IMPDH2 (0.44) | IMPDH2SLC6A2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL12670685 | 0.76 | — | — | |
| SCHEMBL30751833 | 0.75 | IMPDH2 (0.49) | IMPDH2ALDH1A1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112930346-A | Novel compounds as NADPH oxidase inhibitors | 金其尤泰克斯瑞士股份有限公司 | 2021-06-08 | — | — | CN | claimed |
| CN-112930346-A | Novel compounds as NADPH oxidase inhibitors | 金其尤泰克斯瑞士股份有限公司 | 2021-06-08 | — | — | CN | disclosed |