SCHEMBL28586206

SCHEMBL28586206

[c]1ccc(-c2ccc3c4c(cccc24)-c2ccccc2-3)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.48
NFE2L2 Q16236 2/20 0.48
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
ALDH1A1 P00352 5/20 0.42
CASP1 P29466 4/20 0.42
TSHR P16473 3/20 0.42
MAPK1 P28482 3/20 0.42
HSD17B10 Q99714 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HPGD P15428 2/20 0.42
HIF1A Q16665 2/20 0.42
PABPC1 P11940 3/20 0.41
MAPT P10636 3/20 0.41
KDM4E B2RXH2 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ATM Q13315 1/20 0.38
HKDC1 Q2TB90 1/20 0.38
CYP1A2 P05177 4/20 0.34
CYP3A4 P08684 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2338000 0.84 CRHBP (0.42) KEAP1NFE2L2CRHBPCRHR2ALDH1A1
SCHEMBL2033903 0.83 CRHBP (0.56) KEAP1NFE2L2CRHBPCRHR2ALDH1A1
SCHEMBL31107072 0.83 CRHBP (0.56) KEAP1NFE2L2CRHBPCRHR2ALDH1A1
SCHEMBL28787358 0.80 CA12 (0.46) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL28586619 0.79 CRHBP (0.44) KEAP1NFE2L2CRHBPCRHR2ALDH1A1
Water SCHEMBL27550628 0.79 CA12 (0.49) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL161269 0.79 CA12 (0.49) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL1369326 0.79 ALDH1A1 (0.39) KEAP1NFE2L2CRHBPCRHR2ALDH1A1
SCHEMBL1836912 0.78 MAPK1 (0.36) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL27576521 0.78 CA12 (0.47) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed