Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28586233 | 0.86 | RAB9A (0.45) | RAB9AKDM4EFFAR4ERN1ALDH1A1 | |
| SCHEMBL118322 | 0.71 | KDM4E (0.54) | RAB9AKDM4EERN1ALDH1A1BACE1 | |
| SCHEMBL5561673 | 0.66 | ERN1 (0.51) | RAB9AKDM4EERN1ALDH1A1JUN | |
| SCHEMBL5556222 | 0.65 | ERN1 (0.50) | RAB9AKDM4EERN1ALDH1A1JUN | |
| SCHEMBL15329769 | 0.65 | KDM4E (0.55) | RAB9AKDM4EERN1ALDH1A1BACE1 | |
| SCHEMBL11683768 | 0.64 | ERN1 (0.56) | RAB9AKDM4EERN1ALDH1A1JUN | |
| SCHEMBL1400196 | 0.64 | KDM4E (0.51) | RAB9AKDM4EERN1ALDH1A1BACE1 | |
| SCHEMBL20488634 | 0.64 | KDM4E (0.59) | RAB9AKDM4EERN1ALDH1A1JUN | |
| SCHEMBL27945949 | 0.64 | ALDH1A1 (0.56) | RAB9AKDM4EERN1ALDH1A1JUN | |
| SCHEMBL29953044 | 0.64 | SMYD3 (0.47) | RAB9AKDM4EERN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112912371-A | Flavone derivatives for treating and preventing hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2021-06-04 | — | — | CN | disclosed |