Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.56 |
| ▸ | ACE | P12821 | 8/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.46 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.42 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28632127 | 1.00 | MME (0.56) | MMEACESLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28586322 | 1.00 | MME (0.56) | MMEACESLC1A3SLC1A2SLC1A1 | |
| SCHEMBL16232067 | 0.86 | MME (0.59) | MMEACESRRPSAT1 | |
| SCHEMBL598890 | 0.81 | GPR88 (0.49) | MMEACESRRPSAT1 | |
| SCHEMBL21572784 | 0.81 | GPR88 (0.49) | MMEACESRRPSAT1 | |
| SCHEMBL24404055 | 0.81 | GPR88 (0.49) | MMEACESRRPSAT1 | |
| SCHEMBL18574633 | 0.81 | GPR88 (0.49) | MMEACESRRPSAT1 | |
| SCHEMBL609953 | 0.81 | GPR88 (0.49) | MMEACESRRPSAT1 | |
| SCHEMBL597164 | 0.81 | GPR88 (0.49) | MMEACESRRPSAT1 | |
| SCHEMBL18059571 | 0.81 | GPR88 (0.49) | MMEACESRRPSAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135836-A | Preparation method of Sacubitril calcium salt | 鲁南制药集团股份有限公司 | 2021-07-20 | — | — | CN | disclosed |
| CN-113135841-A | Preparation method of Sacubitril intermediate | 鲁南制药集团股份有限公司 | 2021-07-20 | — | — | CN | disclosed |