Sulfuric Acid

Sulfuric Acid

SCHEMBL28586356

O=C(OCCOCCOCCO)c1ccccc1C(=O)OCCOCCOCCO.O=S(=O)(O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.54
ALDH1A1 P00352 9/20 0.51
LMNA P02545 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
TDP1 Q9NUW8 4/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
CYP3A4 P08684 4/20 0.47
MAPK1 P28482 3/20 0.47
TP53 P04637 2/20 0.47
NPC1 O15118 3/20 0.43
HSD17B10 Q99714 3/20 0.43
HPGD P15428 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
GLA P06280 1/20 0.43
HIF1A Q16665 1/20 0.43
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28517439 0.93 TSHR (0.61) TSHRALDH1A1LMNACYP1A2CYP2C9
SCHEMBL31500791 0.93 TSHR (0.61) TSHRALDH1A1LMNACYP1A2CYP2C9
SCHEMBL11496942 0.93 TSHR (0.61) TSHRALDH1A1LMNACYP1A2CYP2C9
SCHEMBL1532574 0.93 TSHR (0.61) TSHRALDH1A1LMNACYP1A2CYP2C9
SCHEMBL207925 0.93 TSHR (0.61) TSHRALDH1A1LMNACYP1A2CYP2C9
SCHEMBL8162965 0.88 TSHR (0.56) TSHRALDH1A1LMNACYP1A2CYP2C9
SCHEMBL29668009 0.87 ALDH1A1 (0.56) TSHRALDH1A1LMNACYP1A2CYP2C9
SCHEMBL185056 0.87 ALDH1A1 (0.56) TSHRALDH1A1LMNACYP1A2CYP2C9
SCHEMBL8578853 0.87 ALDH1A1 (0.56) TSHRALDH1A1LMNACYP1A2CYP2C9
SCHEMBL2458008 0.87 ALDH1A1 (0.56) TSHRALDH1A1LMNACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112903102-B Chip-level spectrometer and preparation method thereof 华中科技大学 2023-02-10 CN claimed
CN-112903102-A Chip-level spectrometer and preparation method thereof 华中科技大学 2021-06-04 CN claimed