Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 11/20 | 0.54 |
| ▸ | RXRB | P28702 | 9/20 | 0.54 |
| ▸ | RXRG | P48443 | 8/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31003834 | 0.93 | RXRA (0.51) | RXRARXRBRXRGNPSR1KMO | |
| SCHEMBL28590408 | 0.89 | RXRA (0.50) | RXRARXRBRXRGNPSR1ALDH1A1 | |
| SCHEMBL28581716 | 0.85 | TAS2R14 (0.43) | RXRARXRBRXRGKMORARB | |
| SCHEMBL28603748 | 0.85 | RXRA (0.40) | RXRARXRBRXRGKMORARG | |
| SCHEMBL28592318 | 0.84 | RXRA (0.39) | RXRARXRBRXRGKMORARG | |
| SCHEMBL28592248 | 0.84 | RXRA (0.42) | RXRARXRBRXRGKMOCYP2C9 | |
| SCHEMBL28603448 | 0.82 | KDM4C (0.44) | RXRARXRBRXRGNPSR1ALDH1A1 | |
| SCHEMBL31003809 | 0.82 | RXRA (0.47) | RXRARXRBRXRGNPSR1KMO | |
| SCHEMBL11570366 | 0.82 | RXRA (0.62) | RXRARXRBRXRGALDH1A1 | |
| SCHEMBL28590237 | 0.81 | NPSR1 (0.38) | RXRARXRBRXRGNPSR1KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121393-A | Aromatic amide compound and application thereof in medicines | 广东东阳光药业有限公司 | 2021-07-16 | — | — | CN | disclosed |