Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11127927 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL7702551 | 0.97 | SLC22A1 (0.55) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL2839296 | 0.97 | SLC22A1 (0.55) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL15973366 | 0.97 | SLC22A1 (0.55) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL11466080 | 0.97 | SLC22A1 (0.55) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL9575880 | 0.95 | SLC22A1 (0.52) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL4895225 | 0.95 | SLC22A1 (0.52) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL491727 | 0.95 | SLC22A1 (0.52) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL721018 | 0.95 | SLC22A1 (0.52) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL4893513 | 0.95 | SLC22A1 (0.52) | ALDH1A1TP53CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1681316-B1 | POLYLACTIC ACID RESIN COMPOSITION, PROCESS FOR PRODUCING THE SAME AND MOLDING THEREOF | TOYOTA MOTOR CO LTD (JP) | 2010-01-20 | — | — | EP | disclosed |
| US-20070032631-A1 | Polylactic acid resin composition, process for producing the same and molding thereof | TJOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2007-02-08 | — | — | US | disclosed |
| US-7084192-B2 | Polylactic acid composite material and molded body | Kabushiki Kaisha Toyota Chuo Kankyusho (JP) | 2006-08-01 | — | — | US | disclosed |
| EP-1681316-A1 | POLYLACTIC ACID RESIN COMPOSITION, PROCESS FOR PRODUCING THE SAME AND MOLDING THEREOF | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2006-07-19 | — | — | EP | disclosed |
| US-20040054051-A1 | Polylactic acid composite material and molded body | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2004-03-18 | — | — | US | disclosed |