Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3620548 | 0.81 | GRM5 (0.51) | PARP1KDM4ETDP1TSHRALDH1A1 | |
| SCHEMBL4186883 | 0.80 | KDM4E (0.65) | PARP1KDM4ETDP1TSHRALDH1A1 | |
| SCHEMBL3646683 | 0.80 | ADORA3 (0.47) | SIRT3SIRT2F7F3SARM1 | |
| SCHEMBL29455925 | 0.80 | GRM5 (0.50) | PARP1KDM4ETDP1TSHRALDH1A1 | |
| SCHEMBL31227852 | 0.79 | BCAT2 (0.53) | SIRT3SIRT2F7F3SARM1 | |
| SCHEMBL45147 | 0.79 | BCAT2 (0.53) | SIRT3SIRT2F7F3SARM1 | |
| SCHEMBL1571384 | 0.79 | MKNK1 (0.55) | SIRT3SIRT2F7F3SARM1 | |
| SCHEMBL30521876 | 0.79 | BCAT2 (0.53) | SIRT3SIRT2F7F3SARM1 | |
| SCHEMBL29575496 | 0.79 | MKNK1 (0.55) | SIRT3SIRT2F7F3SARM1 | |
| SCHEMBL4186880 | 0.77 | TDP1 (0.53) | SIRT3SIRT2F7F3SARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025092884-A1 | METHOD FOR TREATING LEUKEMIA | 深圳市塔吉瑞生物医药有限公司 | 2025-05-08 | — | — | WO | disclosed |
| CN-109651359-B | Substituted nicotinamide compound, pharmaceutical composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2021-06-22 | — | — | CN | disclosed |