Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | LAP3 | P28838 | 4/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 3/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL5901916 | 0.95 | CA2 (0.50) | CA2LAP3MMP1MMP8MMP2 | |
| Phosphoric Acid SCHEMBL571124 | 0.95 | CA2 (0.50) | CA2LAP3MMP1MMP8MMP2 | |
| Phosphoric Acid SCHEMBL15540730 | 0.95 | CA2 (0.50) | CA2LAP3MMP1MMP8MMP2 | |
| Phosphoric Acid SCHEMBL7631550 | 0.91 | CA2 (0.46) | CA2LAP3MMP1MMP8MMP2 | |
| Phosphoric Acid SCHEMBL755803 | 0.91 | CA2 (0.46) | CA2LAP3MMP1MMP8MMP2 | |
| Phosphoric Acid SCHEMBL28697612 | 0.91 | CA2 (0.46) | CA2LAP3MMP1MMP8MMP2 | |
| Phosphoric Acid SCHEMBL497204 | 0.85 | — | — | |
| Phosphoric Acid SCHEMBL8635417 | 0.85 | CA2 (0.60) | CA2LAP3MMP8MMP2FDPS | |
| Phosphoric Acid SCHEMBL28418663 | 0.85 | CA2 (0.60) | CA2LAP3MMP8MMP2FDPS | |
| Phosphoric Acid SCHEMBL20856927 | 0.85 | CA2 (0.60) | CA2LAP3MMP8MMP2FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113151316-B | Method for improving heat resistance of plants by controlling content of MECPP (mecPP) through controlling HDS22 gene | 湖北大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-113151316-A | Method for regulating and controlling content of MECPP (MEcPP) by controlling HDS22 gene so as to improve heat resistance of plants | 湖北大学 | 2021-07-23 | — | — | CN | disclosed |