Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
| ▸ | LIPC | P11150 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601187 | 1.00 | LIPG (0.43) | LIPGEPHX2TEAD1LIPCLIPE | |
| SCHEMBL28592884 | 1.00 | LIPG (0.43) | LIPGEPHX2TEAD1LIPCLIPE | |
| SCHEMBL28586762 | 1.00 | LIPG (0.43) | LIPGEPHX2TEAD1LIPCLIPE | |
| SCHEMBL28593263 | 0.89 | TEAD1 (0.46) | LIPGEPHX2TEAD1LIPCLIPE | |
| SCHEMBL28595462 | 0.88 | EPHX2 (0.46) | EPHX2MMP2MMP13 | |
| SCHEMBL28604577 | 0.87 | LIPG (0.41) | LIPGEPHX2TEAD1LIPCLIPE | |
| SCHEMBL28604581 | 0.87 | LIPG (0.41) | LIPGEPHX2TEAD1LIPCLIPE | |
| SCHEMBL28592578 | 0.86 | LIPG (0.40) | LIPGEPHX2TEAD1LIPCLIPE | |
| SCHEMBL28590716 | 0.86 | LIPG (0.40) | LIPGEPHX2TEAD1LIPCLIPE | |
| SCHEMBL28617818 | 0.86 | LIPG (0.40) | LIPGEPHX2TEAD1LIPCLIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072476-A | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |