Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 16/20 | 0.46 |
| ▸ | FAAH | O00519 | 8/20 | 0.41 |
| ▸ | AADAC | P22760 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28585322 | 0.90 | EPHX2 (0.40) | EPHX2FAAHAADACACHEMMP2 | |
| SCHEMBL28585289 | 0.88 | EPHX2 (0.39) | EPHX2FAAHAADACACHEMMP2 | |
| SCHEMBL28586762 | 0.88 | LIPG (0.43) | EPHX2MMP2MMP13 | |
| SCHEMBL28587244 | 0.88 | LIPG (0.43) | EPHX2MMP2MMP13 | |
| SCHEMBL28601187 | 0.88 | LIPG (0.43) | EPHX2MMP2MMP13 | |
| SCHEMBL28592884 | 0.88 | LIPG (0.43) | EPHX2MMP2MMP13 | |
| SCHEMBL18586394 | 0.86 | GRIN1 (0.44) | EPHX2 | |
| SCHEMBL28615590 | 0.85 | DGAT1 (0.40) | EPHX2 | |
| SCHEMBL28589754 | 0.85 | EPHX2 (0.37) | EPHX2FAAHAADACACHEMMP2 | |
| SCHEMBL13386753 | 0.84 | GRIN1 (0.42) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072476-A | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |