Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15567828 | 0.81 | RAB9A (0.38) | ALDH1A1NPSR1ADRA1AADRA1BGRM6 | |
| SCHEMBL6219929 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDNPSR1KMT2A | |
| SCHEMBL8679491 | 0.78 | NAPRT (0.55) | ALDH1A1KDM4EADRA1AADRA1BGAA | |
| SCHEMBL1566864 | 0.77 | CA12 (0.38) | ALDH1A1ADRA1AADRA1BGRM6 | |
| SCHEMBL163017 | 0.77 | CA12 (0.35) | ALDH1A1ADRA1AADRA1BARKMT2A | |
| SCHEMBL8562952 | 0.76 | ALDH1A1 (0.38) | ALDH1A1ADRA1AADRA1BGRM6 | |
| SCHEMBL5227532 | 0.74 | NAPRT (0.53) | ALDH1A1KDM4EHPGDKMT2AGAA | |
| SCHEMBL624330 | 0.73 | RAB9A (0.33) | ALDH1A1ADRA1AADRA1BKMT2A | |
| SCHEMBL28816343 | 0.73 | ALDH1A1 (0.45) | ALDH1A1KDM4EADRA1AADRA1BGLA | |
| Biphenyl SCHEMBL27272406 | 0.73 | NR4A2 (0.48) | ALDH1A1KDM4EHPGDKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108135168-B | CCR2 modulators | 凯莫森特里克斯股份有限公司 | 2021-07-20 | — | — | CN | disclosed |