Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 15/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | UGCG | Q16739 | 2/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29088047 | 0.91 | TSHR (0.39) | SPHK1SPHK2GBA1UGCGGBA2 | |
| SCHEMBL4592509 | 0.84 | — | — | |
| SCHEMBL4603373 | 0.81 | — | — | |
| SCHEMBL18978571 | 0.78 | SPHK1 (0.43) | SPHK1SPHK2GBA1UGCGGBA2 | |
| SCHEMBL131035 | 0.78 | SPHK1 (0.40) | SPHK1SPHK2GBA1UGCGGBA2 | |
| SCHEMBL130814 | 0.78 | ALDH1A1 (0.57) | SPHK1SPHK2GBA1UGCGGBA2 | |
| SCHEMBL7536085 | 0.77 | NAAA (0.40) | SPHK1SPHK2GBA1UGCGGBA2 | |
| SCHEMBL18978570 | 0.77 | SPHK1 (0.45) | SPHK1SPHK2GBA1UGCGGBA2 | |
| SCHEMBL126800 | 0.76 | TSHR (0.38) | SPHK1SPHK2GBA1UGCGGBA2 | |
| SCHEMBL127440 | 0.76 | ALDH1A1 (0.53) | SPHK1SPHK2GBA1UGCGGBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898286-A | Benzothiophene compound or pharmaceutically acceptable salt and isomer thereof, and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2021-06-04 | — | — | CN | disclosed |