Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11988941 | 0.79 | CES2 (0.58) | CES2CES1LCKFYNDAO | |
| SCHEMBL317582 | 0.77 | CES2 (0.56) | CES2CES1LCKFYNDAO | |
| SCHEMBL9091938 | 0.73 | CES1 (0.48) | CES2CES1DAOMEN1KMT2A | |
| SCHEMBL18088498 | 0.72 | CA2 (0.48) | CES2CES1NPC1RAB9AHDAC1 | |
| SCHEMBL3379216 | 0.71 | CES2 (0.48) | CES2CES1LCKFYNDAO | |
| SCHEMBL3379219 | 0.71 | CES2 (0.48) | CES2CES1LCKFYNDAO | |
| SCHEMBL12431216 | 0.71 | CES2 (0.58) | CES2CES1LCKFYNDAO | |
| SCHEMBL6050171 | 0.71 | — | — | |
| SCHEMBL8614179 | 0.71 | CES1 (0.58) | CES2CES1LCKFYNDAO | |
| SCHEMBL18826040 | 0.70 | CES2 (0.52) | CES2CES1LCKFYNDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024423-B | Beta-fluoro, beta' -bissulfonylimide substituted ketone compound and preparation method and application thereof | 山东领海生物科技有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-113024423-A | Beta-fluoro, beta' -bissulfonylimide substituted ketone compound and preparation method and application thereof | 山东领海生物科技有限公司 | 2021-06-25 | — | — | CN | disclosed |