SCHEMBL28587483

SCHEMBL28587483

C1=Cc2nc3ccccc3nc2CO1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.39
KDM4E B2RXH2 4/20 0.33
ALDH1A1 P00352 4/20 0.33
HSD17B10 Q99714 3/20 0.33
TDP1 Q9NUW8 3/20 0.33
HPGD P15428 2/20 0.33
GAA P10253 2/20 0.33
POLB P06746 4/20 0.32
NQO2 P16083 2/20 0.32
TSHR P16473 2/20 0.31
CASP1 P29466 2/20 0.31
CASP7 P55210 2/20 0.31
MAPK1 P28482 1/20 0.31
GFER P55789 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
PKM P14618 2/20 0.31
ALOX15 P16050 1/20 0.31
PTPN7 P35236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27894937 0.72 ALDH1A1 (0.43) MAPTKDM4EALDH1A1HSD17B10TDP1
SCHEMBL14572406 0.71 MAPT (0.42) MAPTKDM4EALDH1A1HSD17B10TDP1
SCHEMBL16026404 0.71 MAPT (0.37) MAPTKDM4EALDH1A1HSD17B10TDP1
Phenazine SCHEMBL7695162 0.69 MAPT (0.41) MAPTKDM4EALDH1A1HSD17B10TDP1
SCHEMBL11870225 0.69 MAPT (0.50) MAPTKDM4EALDH1A1HSD17B10TDP1
SCHEMBL38102 0.68 MAPT (0.39) MAPTKDM4EALDH1A1HSD17B10TDP1
Oxirane SCHEMBL3048492 0.67 POLB (0.36) MAPTHSD17B10POLBCASP1
SCHEMBL7168253 0.67 MAPT (0.37) MAPTKDM4EALDH1A1HSD17B10TDP1
SCHEMBL13892116 0.67 MAPT (0.37) MAPTKDM4EALDH1A1HSD17B10TDP1
SCHEMBL7168251 0.67 MAPT (0.37) MAPTKDM4EALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112785977-A Pixel circuit and touch display device 友达光电股份有限公司 2021-05-11 CN disclosed