Phenazine

Phenazine

SCHEMBL7695162

O=C1C=Cc2nc3ccccc3nc2C1.c1ccc2nc3ccccc3nc2c1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.41
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
ALDH1A1 P00352 7/20 0.35
RAB9A P51151 4/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
GAA P10253 3/20 0.35
KDM4E B2RXH2 3/20 0.35
POLB P06746 2/20 0.35
PKM P14618 2/20 0.35
NQO2 P16083 3/20 0.34
KMT2A Q03164 3/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NPC1 O15118 3/20 0.32
MEN1 O00255 2/20 0.32
AHR P35869 1/20 0.32
USP2 O75604 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16026404 0.98 MAPT (0.37) MAPTGSK3AGSK3BALDH1A1RAB9A
SCHEMBL29461557 0.73 KDM4E (0.49) MAPTGSK3AGSK3BALDH1A1RAB9A
SCHEMBL3394948 0.73 KDM4E (0.49) MAPTGSK3AGSK3BALDH1A1RAB9A
SCHEMBL2722531 0.71 RAB9A (0.44) MAPTALDH1A1RAB9ASMN1; SMN2GAA
SCHEMBL11526860 0.71 GSK3A (0.40) GSK3AGSK3B
SCHEMBL28587483 0.69 MAPT (0.39) MAPTALDH1A1RAB9ASMN1; SMN2GAA
SCHEMBL14572406 0.68 MAPT (0.42) MAPTALDH1A1RAB9ASMN1; SMN2GAA
SCHEMBL1649779 0.68 MAPT (0.31) MAPTALDH1A1RAB9ASMN1; SMN2GAA
SCHEMBL38102 0.65 MAPT (0.39) MAPTALDH1A1RAB9ASMN1; SMN2GAA
SCHEMBL5347514 0.64 NQO2 (0.41) MAPTALDH1A1RAB9ASMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6348193-B1 Method for inhibiting pathogenic fungi and bacteria in plants using Pseudomonas aureofaciens BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2002-02-19 US disclosed
WO-2001015524-A2 METHOD FOR CONTROLLING BACTERIAL AND FUNGAL DISEASE MICHIGAN STATE UNIVERSITY (US) 2001-03-08 WO disclosed
US-5665351-A APPLYING PURE PSEUDOMONAS CELLS TO GRASS BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 1997-09-09 US disclosed
US-5658794-A ENVIRONMENTALLY SAFE BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 1997-08-19 US disclosed