Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.61 |
| ▸ | F2 | P00734 | 16/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | F11 | P03951 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 3/20 | 0.47 |
| ▸ | F9 | P00740 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29880513 | 1.00 | MASP2 (0.61) | MASP2F2CYP3A4F11F10 | |
| Trifluoroacetic Acid SCHEMBL23452472 | 1.00 | MASP2 (0.61) | MASP2F2CYP3A4F11F10 | |
| Trifluoroacetic Acid SCHEMBL28587648 | 1.00 | MASP2 (0.61) | MASP2F2CYP3A4F11F10 | |
| SCHEMBL23490530 | 0.93 | MASP2 (0.66) | MASP2F2CYP3A4F11F10 | |
| Hydrochloric Acid SCHEMBL23452304 | 0.92 | MASP2 (0.65) | MASP2F2CYP3A4F11F10 | |
| Hydrochloric Acid SCHEMBL23452306 | 0.92 | MASP2 (0.65) | MASP2F2CYP3A4F11F10 | |
| Trifluoroacetic Acid SCHEMBL23454676 | 0.89 | MASP2 (0.60) | MASP2F2CYP3A4F11F10 | |
| Trifluoroacetic Acid SCHEMBL23454672 | 0.89 | MASP2 (0.60) | MASP2F2CYP3A4F11F10 | |
| Trifluoroacetic Acid SCHEMBL28864384 | 0.88 | MASP2 (0.55) | MASP2F2CYP3A4F11F10 | |
| Trifluoroacetic Acid SCHEMBL30131490 | 0.84 | MASP2 (0.55) | MASP2F2CYP3A4F11F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964684-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117964683-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-112867706-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2021-05-28 | — | — | CN | disclosed |