SCHEMBL2858766

SCHEMBL2858766

CCC(=O)OCC(Br)CC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NAAA Q02083 1/20 0.39
HIF1A Q16665 2/20 0.36
ESR1 P03372 1/20 0.36
ALDH1A1 P00352 4/20 0.35
CYP1A2 P05177 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
BLM P54132 1/20 0.35
WRN Q14191 1/20 0.35
TRPA1 O75762 1/20 0.34
RECQL P46063 1/20 0.33
MAPT P10636 1/20 0.33
LMNA P02545 2/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9849668 0.84 ALDH1A1 (0.38) CYP3A4TSHRATMTDP1NAAA
SCHEMBL10835220 0.83 CYP3A4 (0.50) CYP3A4TSHRATMTDP1ALDH1A1
SCHEMBL7976838 0.81
SCHEMBL27927570 0.81 MGAM (0.43) CYP3A4TSHRATMTDP1ALDH1A1
SCHEMBL10837080 0.79
SCHEMBL7982559 0.79
SCHEMBL10835265 0.77 ZDHHC7 (0.38) CYP3A4TSHRATMTDP1ALDH1A1
SCHEMBL2859564 0.77 SMN1; SMN2 (0.33) CYP3A4TSHRATMTDP1ALDH1A1
SCHEMBL29089198 0.77
SCHEMBL14191352 0.76 TSHR (0.52) CYP3A4TSHRATMTDP1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1795581-B1 LUBRICATING OIL COMPOSITION CONTAINING ACRYLIC POLYMER KURARAY CO (JP) 2018-09-19 EP disclosed
US-7718588-B2 Lubricating oil additive containing acrylic polymer and lubricating oil compositions KURARAY CO., LTD. (JP) 2010-05-18 US disclosed
US-20080058234-A1 Lubricating Oil Additive Containing Acrylic Polymer and Lubricating Oil Compositions KURARAY CO., LTD. (JP) 2008-03-06 US disclosed
EP-1795581-A1 LUBRICATING OIL ADDITIVE CONTAINING ACRYLIC POLYMER AND LUBRICATING OIL COMPOSITIONS KURARAY CO., LTD. (JP) 2007-06-13 EP disclosed
US-4568759-A Preparation of epoxides THE DOW CHEMICAL COMPANY (US) 1986-02-04 US disclosed