SCHEMBL2859564

SCHEMBL2859564

CCC(Br)COC(=O)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 4/20 0.32
CYP3A4 P08684 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPT P10636 1/20 0.31
ZDHHC7 Q9NXF8 1/20 0.31
RECQL P46063 1/20 0.30
FAAH O00519 1/20 0.30
TRPA1 O75762 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22597524 0.82 ALDH1A1 (0.35) TSHRTRPA1ALDH1A1
SCHEMBL7982559 0.79
SCHEMBL30932714 0.78 TSHR (0.33) TSHRALDH1A1
SCHEMBL29169945 0.78 TSHR (0.33) TSHRALDH1A1
SCHEMBL10835265 0.77 ZDHHC7 (0.38) SMN1; SMN2TSHRCYP3A4ATMTDP1
SCHEMBL2858766 0.77 CYP3A4 (0.40) TSHRCYP3A4ATMTDP1MAPT
SCHEMBL29089198 0.77
SCHEMBL12414729 0.76 MAPT (0.48) SMN1; SMN2TSHRCYP3A4ATMTDP1
SCHEMBL12413758 0.76 TSHR (0.42) TSHRCYP3A4ATMTDP1MAPT
SCHEMBL28484563 0.76 TSHR (0.32) TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1795581-B1 LUBRICATING OIL COMPOSITION CONTAINING ACRYLIC POLYMER KURARAY CO (JP) 2018-09-19 EP disclosed
US-7718588-B2 Lubricating oil additive containing acrylic polymer and lubricating oil compositions KURARAY CO., LTD. (JP) 2010-05-18 US disclosed
US-20080058234-A1 Lubricating Oil Additive Containing Acrylic Polymer and Lubricating Oil Compositions KURARAY CO., LTD. (JP) 2008-03-06 US disclosed
EP-1795581-A1 LUBRICATING OIL ADDITIVE CONTAINING ACRYLIC POLYMER AND LUBRICATING OIL COMPOSITIONS KURARAY CO., LTD. (JP) 2007-06-13 EP disclosed