Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28583372 | 0.91 | MAPT (0.45) | ALDH1A1LMNASMN1; SMN2MAPTTDP1 | |
| SCHEMBL28575301 | 0.86 | ATM (0.41) | ALDH1A1RAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL29676432 | 0.86 | ATM (0.41) | ALDH1A1RAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL28569109 | 0.83 | SMN1; SMN2 (0.41) | ALDH1A1RAB9ALMNASMN1; SMN2MAPT | |
| SCHEMBL28574975 | 0.82 | MAPT (0.39) | ALDH1A1RAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL29676355 | 0.82 | ATM (0.44) | ALDH1A1RAB9ALMNASMN1; SMN2MAPT | |
| SCHEMBL28570861 | 0.82 | ATM (0.44) | ALDH1A1RAB9ALMNASMN1; SMN2MAPT | |
| SCHEMBL8991985 | 0.80 | ALDH1A1 (0.50) | ALDH1A1RAB9AL3MBTL1LMNAGLA | |
| SCHEMBL5508386 | 0.76 | ATM (0.51) | ALDH1A1L3MBTL1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL11212820 | 0.75 | ATM (0.47) | ALDH1A1RAB9AL3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979658-B | Preparation method of flumazenil | 南湖实验室 | 2022-05-31 | — | — | CN | disclosed |
| CN-112979658-A | Preparation method of flumazenil | 南湖实验室 | 2021-06-18 | — | — | CN | disclosed |