Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SNCA | P37840 | 2/20 | 0.38 |
| ▸ | DTYMK | P23919 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28570861 | 1.00 | ATM (0.44) | ATMTDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29676432 | 0.86 | ATM (0.41) | ATMTDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28575301 | 0.86 | ATM (0.41) | ATMTDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28583372 | 0.84 | MAPT (0.45) | ATMTDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28569109 | 0.83 | SMN1; SMN2 (0.41) | ATMTDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5508386 | 0.83 | ATM (0.51) | ATMTDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28587738 | 0.82 | ALDH1A1 (0.41) | ATMTDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28574975 | 0.82 | MAPT (0.39) | ATMTDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11212820 | 0.79 | ATM (0.47) | ATMTDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31083656 | 0.78 | KMT2A (0.46) | ATMTDP1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979658-B | Preparation method of flumazenil | 南湖实验室 | 2022-05-31 | — | — | CN | disclosed |