Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 10/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 10/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28568388 | 0.97 | ESR2 (0.37) | ESR2ROCK1LPLLIPGRORC | |
| SCHEMBL28577006 | 0.81 | — | — | |
| SCHEMBL14764331 | 0.81 | XDH (0.43) | AR | |
| SCHEMBL1293556 | 0.76 | ESR2 (0.46) | ESR2ROCK1LPLLIPGF11 | |
| SCHEMBL21236344 | 0.76 | ESR2 (0.40) | ESR2ROCK1LPLLIPGF11 | |
| SCHEMBL28576949 | 0.75 | HIF1A (0.40) | ESR2ROCK1LPLLIPGHIF1A | |
| SCHEMBL14764058 | 0.75 | XDH (0.41) | AR | |
| SCHEMBL19991494 | 0.75 | XDH (0.38) | ESR2AR | |
| SCHEMBL2427133 | 0.75 | ESR2 (0.38) | ESR2ROCK1LPLLIPGHIF1A | |
| SCHEMBL12327209 | 0.75 | LIPG (0.44) | ESR2LPLLIPGF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863850-B | Biaryl compound and preparation method and application thereof | 复旦大学 | 2021-05-18 | — | — | CN | disclosed |