SCHEMBL2858786

SCHEMBL2858786

CCC(Cl)COC(=O)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.33
TSHR P16473 3/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL575297 0.81 ALDH1A1 (0.43) TSHRALDH1A1TDP1
SCHEMBL27960340 0.81 ALDH1A1 (0.43) TSHRALDH1A1TDP1
SCHEMBL10835256 0.79
SCHEMBL575298 0.79
SCHEMBL5836751 0.79
SCHEMBL2859445 0.77 NAAA (0.39) TSHRALDH1A1TDP1MAPT
SCHEMBL10836875 0.77 CA1 (0.36) ALDH1A1SMN1; SMN2
SCHEMBL12414729 0.76 MAPT (0.48) TSHRALDH1A1TDP1MAPTSMN1; SMN2
SCHEMBL12413758 0.76 TSHR (0.42) TSHRALDH1A1MAPK1TDP1MAPT
SCHEMBL6060785 0.76 MAPT (0.48) TSHRALDH1A1TDP1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1795581-B1 LUBRICATING OIL COMPOSITION CONTAINING ACRYLIC POLYMER KURARAY CO (JP) 2018-09-19 EP disclosed
US-7718588-B2 Lubricating oil additive containing acrylic polymer and lubricating oil compositions KURARAY CO., LTD. (JP) 2010-05-18 US disclosed
US-20080058234-A1 Lubricating Oil Additive Containing Acrylic Polymer and Lubricating Oil Compositions KURARAY CO., LTD. (JP) 2008-03-06 US disclosed
EP-1795581-A1 LUBRICATING OIL ADDITIVE CONTAINING ACRYLIC POLYMER AND LUBRICATING OIL COMPOSITIONS KURARAY CO., LTD. (JP) 2007-06-13 EP disclosed