Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL832914 | 0.73 | ELANE (0.39) | TOP1ELANEALDH1A1MEN1KMT2A | |
| SCHEMBL28262113 | 0.72 | KDM4E (0.39) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL378548 | 0.72 | KDM4E (0.39) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL27619538 | 0.71 | KDM4E (0.38) | ALDH1A1MAPTKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL6555973 | 0.71 | KDM4E (0.38) | ALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL27619154 | 0.71 | KDM4E (0.38) | ALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL28571880 | 0.65 | PIM3 (0.33) | KMT2A | |
| SCHEMBL27971102 | 0.64 | ALDH1A1 (0.33) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL28583043 | 0.63 | PDPK1 (0.63) | ELANEALDH1A1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL28571883 | 0.62 | ABL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024462-A | Method for efficiently preparing phenanthridinone and derivatives thereof without metal participation | 清华大学 | 2021-06-25 | — | — | CN | disclosed |