SCHEMBL2858813

SCHEMBL2858813

O=[C]C(Cl)C(=O)CCCCl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28490525 0.75
SCHEMBL10878034 0.74
SCHEMBL11771682 0.71
SCHEMBL10669973 0.69
SCHEMBL3678383 0.69
SCHEMBL8432011 0.69
SCHEMBL10804883 0.68
SCHEMBL11129013 0.67 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL4778152 0.64
SCHEMBL27448910 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100120044-A1 MODIFIED POLYNUCLEOTIDES COMPRISING RIBOSE RINGS QIAGEN GMBH (DE) 2010-05-13 US claimed
EP-2142671-A2 MODIFIED POLYNUCLEOTIDES COMPRISING RIBOSE RINGS Qiagen GmbH (DE) 2010-01-13 EP claimed
WO-2008119539-A2 MODIFIED POLYNUCLEOTIDES COMPRISING RIBOSE RINGS QIAGEN GMBH (DE) 2008-10-09 WO claimed
EP-1196631-B1 Modifications of ribonucleic acids CYCLOPS GENOME SCIENCES LTD (GB) 2006-12-06 EP claimed
US-20050272679-A1 Modified polynucleotides and uses thereof CYCLOPS GENOME SCIENCES LIMITED (GB) 2005-12-08 US claimed
US-20030039985-A1 Modified polynucleotides and uses thereof CYCLOPS GENOME SCIENCES LIMITED (GB) 2003-02-27 US claimed
EP-1196631-A1 POLYNUCLEOTIDES Cyclops Genome Sciences Limited (GB) 2002-04-17 EP claimed
WO-2001094626-A1 POLYNUCLEOTIDES CYCLOPS GENOME SCIENCES LIMITED (GB) 2001-12-13 WO claimed
WO-2000075306-A2 METHOD FOR PRODUCING DOUBLE STRANDED POLYNUCLEOTIDES CYCLOPS GENOME SCIENCES LIMITED (GB) 2000-12-14 WO claimed
WO-2000066605-A2 POLYNUCLEOTIDES CYCLOPS GENOME SCIENCES LIMITED (GB) 2000-11-09 WO claimed
US-20100120044-A1 MODIFIED POLYNUCLEOTIDES COMPRISING RIBOSE RINGS QIAGEN GMBH (DE) 2010-05-13 US disclosed
EP-2142671-A2 MODIFIED POLYNUCLEOTIDES COMPRISING RIBOSE RINGS Qiagen GmbH (DE) 2010-01-13 EP disclosed
WO-2008119539-A2 MODIFIED POLYNUCLEOTIDES COMPRISING RIBOSE RINGS QIAGEN GMBH (DE) 2008-10-09 WO disclosed