Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 8/20 | 0.51 |
| ▸ | BRD4 | O60885 | 11/20 | 0.49 |
| ▸ | CECR2 | Q9BXF3 | 5/20 | 0.49 |
| ▸ | TAF1 | P21675 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937472 | 0.93 | BRD4 (0.53) | BRD9BRD4CECR2TAF1 | |
| SCHEMBL17748879 | 0.88 | BRD4 (0.57) | BRD9BRD4CECR2TAF1 | |
| SCHEMBL28963592 | 0.87 | CECR2 (0.59) | BRD9BRD4CECR2TAF1 | |
| SCHEMBL28937471 | 0.85 | CECR2 (0.54) | BRD9BRD4CECR2TAF1 | |
| SCHEMBL28573307 | 0.75 | BRD4 (0.58) | BRD9BRD4CECR2TAF1 | |
| SCHEMBL17749772 | 0.72 | CECR2 (0.56) | BRD9BRD4CECR2TAF1 | |
| SCHEMBL24363753 | 0.69 | BRD4 (0.78) | BRD9BRD4CECR2TAF1 | |
| SCHEMBL17748869 | 0.67 | BRD9 (1.00) | BRD9BRD4CECR2TAF1 | |
| SCHEMBL16382696 | 0.66 | BTK (0.55) | — | |
| SCHEMBL17749785 | 0.66 | BRD4 (1.00) | BRD9BRD4CECR2TAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108614-B | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2021-06-01 | — | — | CN | claimed |
| CN-107108614-B | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2021-06-01 | — | — | CN | disclosed |