Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.58 |
| ▸ | CECR2 | Q9BXF3 | 3/20 | 0.50 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.49 |
| ▸ | TAF1 | P21675 | 2/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.47 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17748879 | 0.87 | BRD4 (0.57) | BRD4CECR2BRD9TAF1TRIM24 | |
| SCHEMBL31590544 | 0.76 | BRD4 (0.65) | BRD4CECR2BRD9TAF1TRIM24 | |
| SCHEMBL28588232 | 0.75 | BRD9 (0.51) | BRD4CECR2BRD9TAF1 | |
| SCHEMBL17748871 | 0.73 | BRD4 (1.00) | BRD4CECR2BRD9TAF1TRIM24 | |
| SCHEMBL28392060 | 0.73 | BRD4 (0.58) | BRD4CECR2BRD9TAF1TRIM24 | |
| SCHEMBL28937472 | 0.73 | BRD4 (0.53) | BRD4CECR2BRD9TAF1 | |
| SCHEMBL28578291 | 0.71 | BRD4 (0.64) | BRD4CECR2BRD9TAF1TRIM24 | |
| SCHEMBL24866050 | 0.71 | BRD4 (0.76) | BRD4CECR2BRD9TAF1 | |
| SCHEMBL28963592 | 0.71 | CECR2 (0.59) | BRD4CECR2BRD9TAF1 | |
| SCHEMBL28937471 | 0.71 | CECR2 (0.54) | BRD4CECR2BRD9TAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108614-B | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2021-06-01 | — | — | CN | claimed |
| CN-107108614-B | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2021-06-01 | — | — | CN | disclosed |