Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 8/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.78 |
| ▸ | MEN1 | O00255 | 7/20 | 0.78 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.78 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.78 |
| ▸ | NPC1 | O15118 | 2/20 | 0.78 |
| ▸ | RAB9A | P51151 | 2/20 | 0.78 |
| ▸ | ATM | Q13315 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 5/20 | 0.67 |
| ▸ | APAF1 | O14727 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | RECQL | P46063 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | CASP6 | P55212 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159132 | 0.86 | POLB (0.65) | USP2KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL14159196 | 0.85 | POLB (0.63) | USP2KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL28593549 | 0.81 | KMT2A (0.66) | USP2KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL12112509 | 0.81 | POLB (1.00) | USP2KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL10792923 | 0.80 | POLB (0.70) | USP2KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL14159197 | 0.78 | USP2 (0.55) | USP2KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL16601645 | 0.78 | POLB (0.85) | USP2KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL887456 | 0.77 | NR1H3 (0.79) | KMT2AMEN1POLBAPAF1ESR1 | |
| SCHEMBL9006289 | 0.77 | KMT2A (0.65) | USP2KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL10701883 | 0.77 | KMT2A (0.59) | USP2KMT2AMEN1KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024463-B | Preparation and application of 1, 8-naphthalimide hydrogen sulfide fluorescent molecular probe | 天津大学 | 2022-05-10 | — | — | CN | claimed |
| CN-113024463-A | Preparation and application of 1, 8-naphthalimide hydrogen sulfide fluorescent molecular probe | 天津大学 | 2021-06-25 | — | — | CN | claimed |
| CN-113024463-B | Preparation and application of 1, 8-naphthalimide hydrogen sulfide fluorescent molecular probe | 天津大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-113024463-A | Preparation and application of 1, 8-naphthalimide hydrogen sulfide fluorescent molecular probe | 天津大学 | 2021-06-25 | — | — | CN | disclosed |